ANNOUNCEMENT

REGULATED INFORMATION DISCLOSURE

The company Diagnostic and Therapeutic Center of Athens HYGEIA SA (hereinafter the “Issuer”) announces that, pursuant to the legislation in force, on February 22, 2018 the company trading as G. APOSTOLOPOULOS HOLDINGS SA and George V. Apostolopoulos submitted to the Hellenic Capital Market Commission and the Issuer a notification dated February 22, 2018 regarding significant changes in the Issuer's voting rights, whereby the following arise:

Reason for submission of notification: Acquisition of voting rights

Company trade name/full name of person subject to notification obligation:

G. APOSTOLOPOULOS HOLDINGS SA and George V. Apostolopoulos

Shareholder trade name: G. APOSTOLOPOULOS HOLDINGS SA

Date when the change in voting rights took place: February 22, 2018

Disclosed details:

STATUS PRIOR TO THE CRITICAL TRANSACTION:

Total percentage of voting rights attached to shares and/or financial instruments: Under 5%

STATUS AFTER THE CRITICAL TRANSACTION:

Total number of voting rights: 15,840,022 attached to shares held directly by G. APOSTOLOPOULOS HOLDINGS SA, which is a company controlled by George V. Apostolopoulos.

Percentage of voting rights attached to shares: 5.181%

Percentage of voting rights arising from financial instruments: 0%